Cross‐sectional associations between use of time and cognition in healthy older adults

Background Physical activity, sedentary behaviour and sleep are independently associated with cognition in older adults. These time-use behaviours not independent, rather, co-dependent parts of the 24-hour day. As such, spending more time one leaves less for others. The balance three day (or composition) should be considered to inform movement guidelines dementia risk reduction populations. Using a compositional data analysis approach, we investigated associations between use sample healthy Method 347 participants (age 60-70 years; 68% female) took part this study. 7 days (time spent sleep, behaviour, light moderate-vigorous physical activity) were captured using accelerometry. Cognition was measured Addenbrooke’s Cognitive Examination III (global cognition) computerized CANTAB tests measuring memory, executive function, fluid reasoning processing speed. outcomes regressed on isometric log ratios (ilrs) compositions, while adjusting age sex demographics, explore potential behaviours. For each outcome, four sets ilr-coordinate systems constructed, different as numerator ratio mean remaining regression coefficient first ilr therefore represented association increasing relative all Result Age negatively performance speed tests. More SB at equal expense other better memory (β = 0.65, p<.01), whilst poorer -0.63, p .02). Spending activity 0.25, .01). Conclusion How adults their is cognition. Findings suggest that moving towards holistic understanding important future prevention strategies.